| Gene Information | |
|---|---|
| Gene Name | ANO7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 933 |
| Protein Names | Anoctamin-7 (Dresden transmembrane protein of the prostate) (D-TMPP) (IPCA-5) (New gene expressed in prostate) (Prostate cancer-associated protein 5) (Transmembrane protein 16G) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 70 ( ENSG00000146205 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6IWH7 |
| Gene Card | ANO7 |
| Uniprot ID | Q6IWH7 |
| Pfam | PF16178; PF04547 |
| In ASD | no |
| Allosteric Prediction | no (-0.474762749) |
| Ortholog in Animals | Alpaca_ ANO7 ( ortholog_one2one ) Dog_ ANO7 ( ortholog_one2one ) Macaque_ ANO7 ( ortholog_one2one ) Mouse_ Ano7 ( ortholog_one2one ) Rat_ Ano7 ( ortholog_one2one ) |
| Ohnologs | ANO2, ANO1, ANO6 |
| Paralogs | ANO8, ANO4, ANO5, ANO2, ANO6, ANO1, ANO10, ANO9, ANO3, PPP1R7 |
| Tissue | prostate |
| Tissue Specificity | Specifically expressed in epithelial cells of the prostate (at protein level). {ECO:0000269|PubMed:14981236, ECO:0000269|PubMed:15761874, ECO:0000269|PubMed:17308099}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2302054 rs7590653 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:14981236, ECO:0000269|PubMed:17308099, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000255}. Cell junction {ECO:0000269|PubMed:17308099}. Endoplasmic reticulum {ECO:0000269|PubMed:22075693}. Note=Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604. {ECO:0000269|PubMed:17308099, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22075693}.; [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:14981236}. |
| Mouse PG classification | NA |
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