| Gene Information | |
|---|---|
| Gene Name | GNAO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Guanine nucleotide-binding protein G(o) subunit alpha |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000087258 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P09471 |
| Gene Card | GNAO1 |
| Uniprot ID | P09471 |
| Pfam | PF00503 |
| In ASD | no |
| Allosteric Prediction | yes (1.219178603) |
| Ortholog in Animals | Macaque_ GNAO1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GNAZ, GNAT1, GNAL, GNA13, GNA12, GNAI2, GNAT2, GNAI3, GNAI1, GNA15, GNA11, GNAT3, GNAS, GNA14, GNAQ |
| Tissue | cerebral.cortex, brain |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6FUF (X-ray 3.12A ) 6G79 (EM 3.78A ) 6K41 (EM 2.90A ) 6OIK (EM 3.60A ) 6WWZ (EM 3.34A ) 7D76 (EM 3.10A ) 7D77 (EM 2.90A ) 7EJ0 (EM 3.20A ) 7EJ8 (EM 3.00A ) 7EJA (EM 3.60A ) 7EJK (EM 3.40A ) 7W2Z (EM 2.80A ) |
| DBSNP | rs886041715 rs587777055 rs587777057 rs886039494 rs886039494 rs797044878 rs797045599 rs1114167431 rs797044951 rs587777054 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:34685729}. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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