| Gene Information | |
|---|---|
| Gene Name | ZFYVE9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1425 |
| Protein Names | Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000157077 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95405 |
| Gene Card | ZFYVE9 |
| Uniprot ID | O95405 |
| Pfam | PF11979; PF01363; PF11409 |
| In ASD | no |
| Allosteric Prediction | no (-0.311666569) |
| Ortholog in Animals | Alpaca_ ZFYVE9 ( ortholog_one2one ) Dog_ ZFYVE9 ( ortholog_one2one ) GuineaPig_ ZFYVE9 ( ortholog_one2one ) Macaque_ ZFYVE9 ( ortholog_one2one ) Mouse_ Zfyve9 ( ortholog_one2one ) Pig_ ZFYVE9 ( ortholog_one2one ) Rat_ Zfyve9 ( ortholog_one2one ) Rabbit_ ZFYVE9 ( ortholog_one2one ) |
| Ohnologs | ZFYVE16 |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002240(Rat);0.085714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DEV (X-ray 2.20A ) 1MK2 (X-ray 2.74A ) 4BKW (X-ray 2.53A ) 5MJY (X-ray 2.25A ) |
| DBSNP | rs9803965 rs3790525 rs11809887 |
| Subcellular location [CC] | Cytoplasm. Early endosome membrane. |
| Mouse PG classification | NA |
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