| Gene Information | |
|---|---|
| Gene Name | RASSF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 369 |
| Protein Names | Ras association domain-containing protein 6 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000169435 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6ZTQ3 |
| Gene Card | RASSF6 |
| Uniprot ID | Q6ZTQ3 |
| Pfam | PF16517; PF00788 |
| In ASD | no |
| Allosteric Prediction | no (-1.059803082) |
| Ortholog in Animals | Alpaca_ RASSF6 ( ortholog_one2one ) Dog_ RASSF6 ( ortholog_one2one ) GuineaPig_ RASSF6 ( ortholog_one2one ) Macaque_ RASSF6 ( ortholog_one2one ) Mouse_ Rassf6 ( ortholog_one2one ) Pig_ RASSF6 ( ortholog_one2one ) Rat_ Rassf6 ( ortholog_one2one ) Rabbit_ RASSF6 ( ortholog_one2one ) |
| Ohnologs | RASSF2, RASSF4 |
| Paralogs | RASSF1, RASSF4, RASSF3, RASSF5, RASSF2 |
| Tissue | brain, kidney, small.intestine |
| Tissue Specificity | Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. {ECO:0000269|PubMed:17404571}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12507775 rs17804499 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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