| Gene Information | |
|---|---|
| Gene Name | ANKRD2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 360 |
| Protein Names | Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000165887 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9GZV1 |
| Gene Card | ANKRD2 |
| Uniprot ID | Q9GZV1 |
| Pfam | PF12796 |
| In ASD | no |
| Allosteric Prediction | no (-1.247433257) |
| Ortholog in Animals | Alpaca_ ANKRD2 ( ortholog_one2one ) Dog_ ANKRD2 ( ortholog_one2one ) GuineaPig_ ANKRD2 ( ortholog_one2one ) Macaque_ ANKRD2 ( ortholog_one2one ) Mouse_ Ankrd2 ( ortholog_one2one ) Pig_ ANKRD2 ( ortholog_one2one ) Rat_ Ankrd2 ( ortholog_one2one ) Rabbit_ ANKRD2 ( ortholog_one2one ) |
| Ohnologs | ANKRD23 |
| Paralogs | ANKRD1 |
| Tissue | heart, skeletal.muscle, left.ventricle |
| Tissue Specificity | Mostly expressed in skeletal and cardiac muscles. Found in slow fibers. Also expressed in kidney, but to a lower extent (at protein level). {ECO:0000269|PubMed:11444853, ECO:0000269|PubMed:11453652}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7094973 |
| Subcellular location [CC] | Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Note=In the sarcoplasm of differentiated striated muscle cells, where it is cytosolic and enriched in the I band. In nucleus and PML bodies of proliferating and undifferentiated myoblasts. Associates with the euchromatin in the nucleus of myocytes upon muscle stress. |
| Mouse PG classification | NA |
| click here to return to the previous page | |