| Gene Information | |
|---|---|
| Gene Name | ANKK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 765 |
| Protein Names | Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (Sugen kinase 288) (SgK288) (X-kinase) |
| Target Name | ankyrin repeat and protein kinase domain-containing protein 1 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000170209 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8NFD2 |
| Gene Card | ANKK1 |
| Uniprot ID | Q8NFD2 |
| Pfam | PF12796; PF13637; PF07714 |
| In ASD | no |
| Allosteric Prediction | no (-0.035795135) |
| Ortholog in Animals | Alpaca_ ANKK1 ( ortholog_one2one ) Dog_ ANKK1 ( ortholog_one2one ) GuineaPig_ ANKK1 ( ortholog_one2one ) Mouse_ Ankk1 ( ortholog_one2one ) Rat_ Ankk1 ( ortholog_one2one ) |
| Ohnologs | RIPK4, RIPK2 |
| Paralogs | RIPK4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain and weakly expressed in placenta and spinal cord. {ECO:0000269|PubMed:14741327, ECO:0000269|PubMed:15146457}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35657708 rs35877321 rs7118900 rs35488601 rs11604671 rs56339158 rs34298987 rs56299709 rs55699907 rs4938016 rs34983219 rs2734849 rs55787008 rs7104979 rs55849504 rs56006094 rs1800497 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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