| Gene Information | |
|---|---|
| Gene Name | ANKFY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1169 |
| Protein Names | Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000185722 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9P2R3 |
| Gene Card | ANKFY1 |
| Uniprot ID | Q9P2R3 |
| Pfam | PF00023; PF12796; PF13637; PF13857; PF00651; PF01363 |
| In ASD | no |
| Allosteric Prediction | no (-0.745799755) |
| Ortholog in Animals | Alpaca_ ANKFY1 ( ortholog_one2one ) Dog_ ANKFY1 ( ortholog_one2one ) GuineaPig_ ANKFY1 ( ortholog_one2one ) Macaque_ ANKFY1 ( ortholog_one2one ) Mouse_ Ankfy1 ( ortholog_one2one ) Pig_ ANKFY1 ( ortholog_one2one ) Rat_ Ankfy1 ( ortholog_one2one ) Rabbit_ ANKFY1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | High expression in whole adult brain and intermediate expression in all other tissues and specific brain regions examined, including fetal brain. {ECO:0000269|PubMed:10574462, ECO:0000269|PubMed:10940552}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.020094(Mouse);NULL(Rat);0.020000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10940552}. Endosome membrane {ECO:0000269|PubMed:10940552}; Peripheral membrane protein {ECO:0000269|PubMed:10940552}. Early endosome {ECO:0000269|PubMed:15328530}. Note=Also associated with endosomal membranes. Localizes to macropinosomes. {ECO:0000269|PubMed:15328530}. |
| Mouse PG classification | NA |
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