| Gene Information | |
|---|---|
| Gene Name | HBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPI-HBP1) (GPI-anchored HDL-binding protein 1) (High density lipoprotein-binding protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105856 ) 3 ( ENSG00000283847 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IV16 |
| Gene Card | GPIHBP1 |
| Uniprot ID | Q8IV16 |
| Pfam | PF00021 |
| In ASD | no |
| Allosteric Prediction | yes (0.101022318) |
| Ortholog in Animals | Alpaca_ HBP1 ( ortholog_one2one ) Dog_ HBP1 ( ortholog_one2one ) GuineaPig_ HBP1 ( ortholog_one2one ) Macaque_ HBP1 ( ortholog_one2one ) Mouse_ Hbp1 ( ortholog_one2one ) Pig_ HBP1 ( ortholog_one2one ) Rat_ Hbp1 ( ortholog_one2one ) Rabbit_ HBP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6E7K (X-ray 2.80A ) 6OAU (X-ray 2.48A ) 6OAZ (X-ray 3.04A ) 6OB0 (X-ray 2.81A ) |
| DBSNP | rs11538389 rs587777636 rs587777638 rs587777638 rs587777639 rs587777639 rs587777640 rs587777637 rs78367243 rs145844329 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Cell membrane {ECO:0000269|PubMed:19304573}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. |
| Mouse PG classification | NA |
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