Gene Information
Gene NameANGPT4
OrganismHomo sapiens (Human)
Gene Length503
Protein NamesAngiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000101280 )
Evolutionary StageMammalia
AlphaFoldDBQ9Y264
Gene CardANGPT4
Uniprot IDQ9Y264
PfamPF00147
In ASDno
Allosteric Predictionyes (0.061097177)
Ortholog in AnimalsAlpaca_ ANGPT4 ( ortholog_one2one )
Dog_ ANGPT4 ( ortholog_one2one )
Macaque_ ANGPT4 ( ortholog_one2one )
Mouse_ Angpt4 ( ortholog_one2one )
Pig_ ANGPT4 ( ortholog_one2one )
Rat_ Angpt4 ( ortholog_one2one )
Rabbit_ ANGPT4 ( ortholog_one2one )
OhnologsANGPT1
ParalogsTNC, FCN1, ANGPTL5, FGL1, FCN2, ANGPTL4, FIBCD1, TNN, ANGPTL6, TNXB, FGB, ANGPTL1, MFAP4, TNR, ANGPTL3, FGA, ANGPTL2, ANGPTL7, FCN3, FNDC7, FGL2, FGG, ANGPT1, FN1, ANGPT2
TissueNA
Tissue SpecificityHighly expressed in the lung with much lower levels found in other tissues.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs869171 
Subcellular location [CC]Secreted {ECO:0000305}.
Mouse PG classificationNA
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