| Gene Information | |
|---|---|
| Gene Name | ANGPT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 498 |
| Protein Names | Angiopoietin-1 (ANG-1) |
| Target Name | angiopoietin-1 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000154188 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q15389 |
| Gene Card | ANGPT1 |
| Uniprot ID | Q15389 |
| Pfam | PF00147 |
| In ASD | no |
| Allosteric Prediction | yes (0.4302889) |
| Ortholog in Animals | Alpaca_ ANGPT1 ( ortholog_one2one ) Dog_ ANGPT1 ( ortholog_one2one ) GuineaPig_ ANGPT1 ( ortholog_one2one ) Macaque_ ANGPT1 ( ortholog_one2one ) Mouse_ Angpt1 ( ortholog_one2one ) Pig_ ANGPT1 ( ortholog_one2one ) Rat_ Angpt1 ( ortholog_one2one ) Rabbit_ ANGPT1 ( ortholog_one2one ) |
| Ohnologs | ANGPT4, ANGPT2 |
| Paralogs | TNC, FCN1, ANGPTL5, FGL1, FCN2, ANGPTL4, FIBCD1, TNN, ANGPTL6, TNXB, FGB, ANGPT4, ANGPTL1, MFAP4, TNR, ANGPTL3, FGA, ANGPTL2, ANGPTL7, FCN3, FNDC7, FGL2, FGG, FN1, ANGPT2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4EPU (X-ray 2.10A ) 4JYO (X-ray 2.50A ) 4K0V (X-ray 4.51A ) |
| DBSNP | rs777414772 rs73701083 rs377442517 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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