| Gene Information | |
|---|---|
| Gene Name | PPP2R2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 447 |
| Protein Names | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) |
| Target Name | serine/threonine-protein phosphatase 2a 55 kda regulatory subunit b alpha isoform |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000221914 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P63151 |
| Gene Card | PPP2R2A |
| Uniprot ID | P63151 |
| Pfam | NA |
| In ASD | yes |
| Allosteric Prediction | yes (0.741588739) |
| Ortholog in Animals | Alpaca_ PPP2R2A ( ortholog_one2one ) Dog_ PPP2R2A ( ortholog_one2one ) GuineaPig_ PPP2R2A ( ortholog_one2one ) Macaque_ PPP2R2A ( ortholog_one2one ) Mouse_ Ppp2r2a ( ortholog_one2one ) Pig_ PPP2R2A ( ortholog_one2one ) Rat_ Ppp2r2a ( ortholog_one2one ) Rabbit_ PPP2R2A ( ortholog_one2one ) |
| Ohnologs | PPP2R2D, PPP2R2C, PPP2R2B |
| Paralogs | PPP2R2D, PPP2R2B, PPP2R2C |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined. {ECO:0000269|PubMed:1849734}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.170720(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3DW8 (X-ray 2.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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