| Gene Information | |
|---|---|
| Gene Name | AMPH |
| Organism | Homo sapiens (Human) |
| Gene Length | 695 |
| Protein Names | Amphiphysin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000078053 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49418 |
| Gene Card | AMPH |
| Uniprot ID | P49418 |
| Pfam | PF03114; PF14604 |
| In ASD | no |
| Allosteric Prediction | yes (0.1985676) |
| Ortholog in Animals | Alpaca_ AMPH ( ortholog_one2one ) Dog_ AMPH ( ortholog_one2one ) GuineaPig_ AMPH ( ortholog_one2one ) Macaque_ AMPH ( ortholog_one2one ) Mouse_ Amph ( ortholog_one2one ) Pig_ AMPH ( ortholog_one2one ) Rat_ Amph ( ortholog_one2one ) Rabbit_ AMPH ( ortholog_one2one ) |
| Ohnologs | BIN1 |
| Paralogs | BIN1, BIN3, BIN2 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Neurons, certain endocrine cell types and spermatocytes. |
| Pharmacological Animal Models | 0.116162(Chimpanzee);NULL(Mouse);NULL(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KY7 (X-ray 2.15A ) 1UTC (X-ray 2.30A ) 3SOG (X-ray 2.30A ) 4ATM (X-ray 1.78A ) 5M5S (X-ray 1.88A ) 5M61 (X-ray 1.84A ) |
| DBSNP | rs35166354 rs17171345 rs35024632 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. |
| Mouse PG classification | NA |
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