Gene Information
Gene NameCPTP
OrganismHomo sapiens (Human)
Gene Length214
Protein NamesCeramide-1-phosphate transfer protein (CPTP) (Glycolipid transfer protein domain-containing protein 1) (GLTP domain-containing protein 1)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000224051 )
Evolutionary StageEukaryota
AlphaFoldDBQ5TA50
Gene CardCPTP
Uniprot IDQ5TA50
PfamPF08718
In ASDno
Allosteric Predictionno (-0.891881988)
Ortholog in AnimalsAlpaca_ CPTP ( ortholog_one2one )
Dog_ CPTP ( ortholog_one2one )
GuineaPig_ CPTP ( ortholog_one2one )
Macaque_ CPTP ( ortholog_one2one )
Mouse_ Cptp ( ortholog_one2one )
Rat_ Cptp ( ortholog_one2many )
OhnologsNA
ParalogsGLTPD2, CERT1, PLEKHA8, GLTP, PLEKHA3
TissueNA
Tissue SpecificityUbiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:23863933}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4K80  (X-ray  2.05A  )  4K84  (X-ray  1.90A  )  4K85  (X-ray  1.90A  )  4K8N  (X-ray  3.10A  )  4KBS  (X-ray  1.90A  )  4KF6  (X-ray  3.20A  ) 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytosol {ECO:0000269|PubMed:23863933}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:23863933};
Peripheral membrane protein {ECO:0000269|PubMed:23863933}. Cell membrane {ECO:0000269|PubMed:23863933};
Peripheral membrane protein {ECO:0000269|PubMed:23863933};
Cytoplasmic side {ECO:0000269|PubMed:23863933}. Endosome membrane {ECO:0000269|PubMed:23863933};
Peripheral membrane protein {ECO:0000269|PubMed:23863933}. Nucleus outer membrane {ECO:0000269|PubMed:23863933};
Peripheral membrane protein {ECO:0000269|PubMed:23863933}.
Mouse PG classificationNA
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