| Gene Information | |
|---|---|
| Gene Name | GPR173 |
| Organism | Homo sapiens (Human) |
| Gene Length | 373 |
| Protein Names | Probable G-protein coupled receptor 173 (Super conserved receptor expressed in brain 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184194 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NS66 |
| Gene Card | GPR173 |
| Uniprot ID | Q9NS66 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.334632541) |
| Ortholog in Animals | Alpaca_ GPR173 ( ortholog_one2one ) Dog_ GPR173 ( ortholog_one2many ) GuineaPig_ GPR173 ( ortholog_one2one ) Macaque_ GPR173 ( ortholog_one2one ) Mouse_ Gpr173 ( ortholog_one2one ) Pig_ GPR173 ( ortholog_one2one ) Rat_ AABR07037489.1 ( ortholog_one2one ) Rabbit_ GPR173 ( ortholog_one2one ) |
| Ohnologs | GPR85, GPR27 |
| Paralogs | GPR27, GPR85 |
| Tissue | NA |
| Tissue Specificity | Expressed in the ovary, specifically in granulosa cells of follicles that have passed the primary stage and in oocytes (at protein level) (PubMed:30933929). Expressed at high levels in brain. Lower levels in small intestine. In brain regions, detected in all regions tested. Highest levels in the cerebellum and cerebral cortex. {ECO:0000269|PubMed:30933929}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |