| Gene Information | |
|---|---|
| Gene Name | AML1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 453 |
| Protein Names | Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q01196 |
| Gene Card | RUNX1 |
| Uniprot ID | Q01196 |
| Pfam | PF00853; PF08504 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.009187(Mouse);NULL(Rat);0.021053(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CMO (NMR - ) 1CO1 (NMR - ) 1E50 (X-ray 2.60A ) 1H9D (X-ray 2.60A ) 1LJM (X-ray 2.50A ) |
| DBSNP | rs1060499616 rs74315450 rs1055308 rs1055309 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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