| Gene Information | |
|---|---|
| Gene Name | AMIGO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 522 |
| Protein Names | Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139211 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86SJ2 |
| Gene Card | AMIGO2 |
| Uniprot ID | Q86SJ2 |
| Pfam | PF00047; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.390056727) |
| Ortholog in Animals | Alpaca_ AMIGO2 ( ortholog_one2one ) Dog_ AMIGO2 ( ortholog_one2one ) GuineaPig_ AMIGO2 ( ortholog_one2one ) Macaque_ AMIGO2 ( ortholog_one2one ) Mouse_ Amigo2 ( ortholog_one2one ) Pig_ AMIGO2 ( ortholog_one2one ) Rat_ Amigo2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AMIGO1, AMIGO3 |
| Tissue | NA |
| Tissue Specificity | Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers. {ECO:0000269|PubMed:15107827}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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