| Gene Information | |
|---|---|
| Gene Name | DDX47 |
| Organism | Homo sapiens (Human) |
| Gene Length | 455 |
| Protein Names | Probable ATP-dependent RNA helicase DDX47 (EC 3.6.4.13) (DEAD box protein 47) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000213782 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H0S4 |
| Gene Card | DDX47 |
| Uniprot ID | Q9H0S4 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | no (-1.193938599) |
| Ortholog in Animals | Alpaca_ DDX47 ( ortholog_one2one ) Dog_ DDX47 ( ortholog_one2one ) GuineaPig_ DDX47 ( ortholog_one2one ) Macaque_ DDX47 ( ortholog_one2one ) Mouse_ Ddx47 ( ortholog_one2one ) Pig_ DDX47 ( ortholog_one2one ) Rat_ Ddx47 ( ortholog_one2one ) Rabbit_ DDX47 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | Expressed in skin, lung and breast. Also expressed in the brain. {ECO:0000269|PubMed:31256877}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3BER (X-ray 1.40A ) |
| DBSNP | rs577622688 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:16963496}. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis. |
| Mouse PG classification | NA |
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