| Gene Information | |
|---|---|
| Gene Name | AMD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] |
| Target Name | s-adenosylmethionine decarboxylase proenzyme |
| Target Type | Successful target |
| Gene Age | 950 ( ENSG00000123505 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P17707 |
| Gene Card | AMD1 |
| Uniprot ID | P17707 |
| Pfam | PF01536 |
| In ASD | yes |
| Allosteric Prediction | yes (0.604288535) |
| Ortholog in Animals | Alpaca_ AMD1 ( ortholog_one2one ) Dog_ AMD1 ( ortholog_one2one ) GuineaPig_ AMD1 ( ortholog_one2one ) Macaque_ AMD1 ( ortholog_one2one ) Mouse_ Amd1 ( ortholog_one2many ) Mouse_ Amd2 ( ortholog_one2many ) Rat_ Amd1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1I72 (X-ray 2.00A ) 1I79 (X-ray 2.01A ) 1I7B (X-ray 1.90A ) 1I7C (X-ray 2.40A ) 1I7M (X-ray 2.24A ) 1JEN (X-ray 2.25A ) 1JL0 (X-ray 1.50A ) 1MSV (X-ray 1.75A ) 3DZ2 (X-ray 1.86A ) 3DZ3 (X-ray 2.62A ) 3DZ4 (X-ray 1.84A ) 3DZ5 (X-ray 2.43A ) 3DZ6 (X-ray 1.83A ) 3DZ7 (X-ray 1.91A ) 3EP3 (X-ray 1.84A ) 3EP4 (X-ray 1.89A ) 3EP5 (X-ray 1.99A ) 3EP6 (X-ray 1.70A ) 3EP7 (X-ray 2.00A ) 3EP8 (X-ray 1.97A ) 3EP9 (X-ray 2.35A ) 3EPA (X-ray 2.10A ) 3EPB (X-ray 1.75A ) 3H0V (X-ray 2.24A ) 3H0W (X-ray 1.81A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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