| Gene Information | |
|---|---|
| Gene Name | ALX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | Homeobox protein aristaless-like 4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000052850 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H161 |
| Gene Card | ALX4 |
| Uniprot ID | Q9H161 |
| Pfam | PF00046; PF03826 |
| In ASD | no |
| Allosteric Prediction | no (-1.79573935) |
| Ortholog in Animals | Alpaca_ ALX4 ( ortholog_one2one ) Dog_ ALX4 ( ortholog_one2one ) GuineaPig_ ALX4 ( ortholog_one2one ) Macaque_ ALX4 ( ortholog_one2one ) Mouse_ Alx4 ( ortholog_one2one ) Pig_ ALX4 ( ortholog_one2one ) Rat_ Alx4 ( ortholog_one2one ) Rabbit_ ALX4 ( ortholog_one2one ) |
| Ohnologs | ALX1, ALX3 |
| Paralogs | ARGFX, PAX7, PAX3, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | Expression is likely to be restricted to bone. Found in parietal bone. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2M0C (NMR - ) |
| DBSNP | rs281865153 rs3824915 rs12421995 rs281865154 rs104894193 rs3824915 rs104894196 rs149897209 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:19692347}. |
| Mouse PG classification | HPG |
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