| Gene Information | |
|---|---|
| Gene Name | ALX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 326 |
| Protein Names | ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000180318 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15699 |
| Gene Card | ALX1 |
| Uniprot ID | Q15699 |
| Pfam | PF00046; PF03826 |
| In ASD | no |
| Allosteric Prediction | no (-1.096338918) |
| Ortholog in Animals | Alpaca_ ALX1 ( ortholog_one2one ) Dog_ ALX1 ( ortholog_one2one ) GuineaPig_ ALX1 ( ortholog_one2one ) Mouse_ Alx1 ( ortholog_one2one ) Pig_ ALX1 ( ortholog_one2one ) Rat_ Alx1 ( ortholog_one2one ) Rabbit_ ALX1 ( ortholog_one2one ) |
| Ohnologs | ALX4, ALX3 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, PRRX1, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | Cartilage and cervix tissue. {ECO:0000269|PubMed:8756334}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:8756334, ECO:0000269|PubMed:9753625}. |
| Mouse PG classification | HPG |
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