| Gene Information | |
|---|---|
| Gene Name | TMEM123 |
| Organism | Homo sapiens (Human) |
| Gene Length | 208 |
| Protein Names | Porimin (Keratinocytes-associated transmembrane protein 3) (KCT-3) (Pro-oncosis receptor inducing membrane injury) (Transmembrane protein 123) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000152558 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N131 |
| Gene Card | TMEM123 |
| Uniprot ID | Q8N131 |
| Pfam | PF05283 |
| In ASD | no |
| Allosteric Prediction | no (-1.450393891) |
| Ortholog in Animals | Alpaca_ TMEM123 ( ortholog_one2one ) Dog_ TMEM123 ( ortholog_one2one ) Macaque_ TMEM123 ( ortholog_one2one ) Mouse_ Tmem123 ( ortholog_one2one ) Rat_ Tmem123 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD164, CD164L2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. {ECO:0000269|PubMed:11481458, ECO:0000269|PubMed:12752121}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2155587 rs11547915 rs12288849 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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