| Gene Information | |
|---|---|
| Gene Name | ACSL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 720 |
| Protein Names | Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000123983 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95573 |
| Gene Card | ACSL3 |
| Uniprot ID | O95573 |
| Pfam | PF00501 |
| In ASD | no |
| Allosteric Prediction | yes (0.684667386) |
| Ortholog in Animals | Alpaca_ ACSL3 ( ortholog_one2one ) GuineaPig_ ACSL3 ( ortholog_one2one ) Macaque_ ACSL3 ( ortholog_one2one ) Mouse_ Acsl3 ( ortholog_one2one ) Pig_ ACSL3 ( ortholog_one2one ) Rat_ Acsl3 ( ortholog_one2one ) Rabbit_ ACSL3 ( ortholog_one2one ) |
| Ohnologs | ACSL4 |
| Paralogs | SLC27A4, ACSBG1, ACSL1, SLC27A3, ACSL6, ACSBG2, SLC27A6, ACSL4, ACSL5, SLC27A2, SLC27A1, SLC27A5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1046032 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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