| Gene Information | |
|---|---|
| Gene Name | MSH5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 834 |
| Protein Names | MutS protein homolog 5 (hMSH5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000204410 ) 3 ( ENSG00000227314 ) 3 ( ENSG00000230293 ) 3 ( ENSG00000230961 ) 3 ( ENSG00000233345 ) 3 ( ENSG00000235222 ) 3 ( ENSG00000235569 ) 3 ( ENSG00000237333 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43196 |
| Gene Card | MSH5 |
| Uniprot ID | O43196 |
| Pfam | PF05192; PF05190; PF00488 |
| In ASD | no |
| Allosteric Prediction | no (-0.043486488) |
| Ortholog in Animals | Alpaca_ MSH5 ( ortholog_one2one ) Dog_ MSH5 ( ortholog_one2one ) GuineaPig_ MSH5 ( ortholog_one2one ) Macaque_ MSH5 ( ortholog_one2one ) Mouse_ Msh5 ( ortholog_one2one ) Pig_ MSH5 ( ortholog_one2one ) Rat_ Msh5 ( ortholog_one2one ) Rabbit_ MSH5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MSH3, MSH2, MSH6, MSH4 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with high levels in testis and ovary, including granulosa cells (PubMed:9740671, PubMed:28175301). Also expressed in fetal ovary and adrenal gland (PubMed:28175301). {ECO:0000269|PubMed:28175301, ECO:0000269|PubMed:9740671}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2075789 rs28381349 rs28381358 rs28381359 rs28399976 rs28399977 rs1060505055 rs752657544 rs1802127 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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