| Gene Information | |
|---|---|
| Gene Name | ALDOA |
| Organism | Homo sapiens (Human) |
| Gene Length | 364 |
| Protein Names | Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) |
| Target Name | fructose-bisphosphate aldolase a |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000149925 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P04075 |
| Gene Card | ALDOA |
| Uniprot ID | P04075 |
| Pfam | PF00274 |
| In ASD | yes |
| Allosteric Prediction | yes (1.243139728) |
| Ortholog in Animals | Alpaca_ ALDOA ( ortholog_one2one ) Dog_ ALDOA ( ortholog_one2many ) GuineaPig_ ALDOA ( ortholog_one2one ) Macaque_ ALDOA ( ortholog_one2one ) Mouse_ Aldoa ( ortholog_one2many ) Mouse_ Aldoart2 ( ortholog_one2many ) Mouse_ Aldoart1 ( ortholog_one2many ) Pig_ ALDOA ( ortholog_one2one ) Rat_ Aldoa ( ortholog_one2many ) Rat_ Aldoart2 ( ortholog_one2many ) Rabbit_ ALDOA ( ortholog_one2one ) |
| Ohnologs | ALDOC, ALDOB |
| Paralogs | ALDOC, ALDOB |
| Tissue | artery |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ALD (X-ray 2.00A ) 2ALD (X-ray 2.10A ) 4ALD (X-ray 2.80A ) 5KY6 (X-ray 1.94A ) 6XMH (X-ray 1.95A ) 6XML (X-ray 1.88A ) 6XMM (X-ray 2.11A ) 6XMO (X-ray 2.60A ) |
| DBSNP | rs11553107 rs121909533 rs11553108 rs121909534 rs138824667 |
| Subcellular location [CC] | Cytoplasm, myofibril, sarcomere, I band {ECO:0000250|UniProtKB:P00883}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:P00883}. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+). {ECO:0000250|UniProtKB:P00883}. |
| Mouse PG classification | NA |
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