| Gene Information | |
|---|---|
| Gene Name | PIP4K2C |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (EC 2.7.1.149) (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma) |
| Target Name | phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000166908 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TBX8 |
| Gene Card | PIP4K2C |
| Uniprot ID | Q8TBX8 |
| Pfam | PF01504 |
| In ASD | no |
| Allosteric Prediction | yes (0.064280094) |
| Ortholog in Animals | Alpaca_ PIP4K2C ( ortholog_one2one ) Dog_ PIP4K2C ( ortholog_one2one ) GuineaPig_ PIP4K2C ( ortholog_one2one ) Macaque_ PIP4K2C ( ortholog_one2one ) Mouse_ Pip4k2c ( ortholog_one2one ) Pig_ PIP4K2C ( ortholog_one2one ) Rat_ Pip4k2c ( ortholog_one2one ) Rabbit_ PIP4K2C ( ortholog_one2one ) |
| Ohnologs | PIP4K2A |
| Paralogs | PIP5K1A, PIP5KL1, PIP5K1B, PIP4K2B, PIP5K1C, PIP4K2A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2GK9 (X-ray 2.80A ) 7QIE (X-ray 2.39A ) |
| DBSNP | rs17550713 rs17852569 rs2277319 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:O88370}. Cytoplasm {ECO:0000250|UniProtKB:O88370}. |
| Mouse PG classification | NA |
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