Gene Information
Gene NameALDH1L2
OrganismHomo sapiens (Human)
Gene Length923
Protein NamesMitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000136010 )
Evolutionary StageEumetazoa
AlphaFoldDBQ3SY69
Gene CardALDH1L2
Uniprot IDQ3SY69
PfamPF00171; PF02911; PF00551; PF00550
In ASDno
Allosteric Predictionno (-0.623785603)
Ortholog in AnimalsAlpaca_ ALDH1L2 ( ortholog_one2one )
Dog_ ALDH1L2 ( ortholog_one2one )
GuineaPig_ ALDH1L2 ( ortholog_one2one )
Macaque_ ALDH1L2 ( ortholog_one2one )
Mouse_ Aldh1l2 ( ortholog_one2one )
Pig_ ALDH1L2 ( ortholog_one2one )
Rat_ Aldh1l2 ( ortholog_one2one )
Rabbit_ ALDH1L2 ( ortholog_one2one )
OhnologsALDH1L1
ParalogsALDH7A1, ALDH1B1, ALDH3A2, ALDH1A1, ALDH3B1, ALDH3B2, ALDH3A1, ALDH2, ALDH9A1, ALDH1A2, ALDH6A1, ALDH5A1, ALDH1L1, ALDH1A3, ALDH8A1, ALDH4A1, ALDH16A1
Tissuepancreas, parotid.gland, adipose.tissue
Tissue SpecificityHighly expressed in pancreas, heart, brain and skeletal muscle. {ECO:0000269|PubMed:20498374}.
Pharmacological Animal Models0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion {ECO:0000269|PubMed:20498374}.
Mouse PG classificationNA
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