| Gene Information | |
|---|---|
| Gene Name | MTF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 593 |
| Protein Names | Metal-response element-binding transcription factor 2 (Metal regulatory transcription factor 2) (Metal-response element DNA-binding protein M96) (Polycomb-like protein 2) (hPCl2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143033 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y483 |
| Gene Card | MTF2 |
| Uniprot ID | Q9Y483 |
| Pfam | PF14061; PF00628; PF18104 |
| In ASD | no |
| Allosteric Prediction | yes (0.649792826) |
| Ortholog in Animals | Alpaca_ MTF2 ( ortholog_one2one ) Dog_ MTF2 ( ortholog_one2one ) GuineaPig_ MTF2 ( ortholog_one2one ) Macaque_ MTF2 ( ortholog_one2one ) Mouse_ Mtf2 ( ortholog_one2one ) Pig_ MTF2 ( ortholog_one2one ) Rat_ Mtf2 ( ortholog_one2one ) Rabbit_ MTF2 ( ortholog_one2one ) |
| Ohnologs | PHF1, PHF19 |
| Paralogs | PHF19, PHF1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.054545(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XFR (X-ray 2.25A ) |
| DBSNP | rs2815427 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:31959557}. Note=Localizes to chromatin as part of the PRC2 complex. {ECO:0000269|PubMed:31959557}. |
| Mouse PG classification | NA |
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