| Gene Information | |
|---|---|
| Gene Name | AKR7L |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000211454 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NHP1 |
| Gene Card | AKR7L |
| Uniprot ID | Q8NHP1 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | Dog_ AKR7L ( ortholog_one2one ) GuineaPig_ AKR7L ( ortholog_one2one ) Mouse_ Akr7a5 ( ortholog_one2one ) Pig_ AKR7A2 ( ortholog_one2one ) Rat_ Akr7a2 ( ortholog_one2one ) Rabbit_ AKR7L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKR1C8, AKR7A3, KCNAB1, KCNAB3, AKR7A2, AKR1C3, AKR1C1, AKR1B1, AKR1E2, AKR1C4, AKR1A1, AKR1C2, AKR1B15, AKR1B10, KCNAB2, AKR1D1 |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in uterus. {ECO:0000269|PubMed:12879023}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2235795 rs2982534 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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