| Gene Information | |
|---|---|
| Gene Name | AKR7A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000162482 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95154 |
| Gene Card | AKR7A3 |
| Uniprot ID | O95154 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | no (-0.44399387) |
| Ortholog in Animals | Alpaca_ AKR7A3 ( ortholog_one2one ) Macaque_ AKR7A3 ( ortholog_one2one ) Rat_ Akr7a3 ( ortholog_one2one ) Rabbit_ AKR7A3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKR1C8, KCNAB1, KCNAB3, AKR7A2, AKR1C3, AKR1C1, AKR1B1, AKR1E2, AKR1C4, AKR1A1, AKR1C2, AKR1B15, AKR1B10, KCNAB2, AKR7L, AKR1D1 |
| Tissue | pancreas, stomach |
| Tissue Specificity | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. {ECO:0000269|PubMed:12879023, ECO:0000269|PubMed:18416522}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CLP (X-ray 3.00A ) |
| DBSNP | rs2231198 rs1738023 rs1738025 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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