| Gene Information | |
|---|---|
| Gene Name | AKR1E2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | 1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000165568 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q96JD6 |
| Gene Card | AKR1E2 |
| Uniprot ID | Q96JD6 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | no (-1.001184095) |
| Ortholog in Animals | Alpaca_ AKR1E2 ( ortholog_one2one ) Dog_ AKR1E2 ( ortholog_one2one ) GuineaPig_ AKR1E2 ( ortholog_one2one ) Macaque_ AKR1E2 ( ortholog_one2one ) Mouse_ Akr1e1 ( ortholog_one2one ) Pig_ AKR1E2 ( ortholog_one2one ) Rat_ Akr1e2 ( ortholog_one2one ) Rabbit_ AKR1E2 ( ortholog_one2one ) |
| Ohnologs | AKR1B1, AKR1B10 |
| Paralogs | AKR1B1, AKR1C8, AKR7A3, KCNAB1, KCNAB3, AKR7A2, AKR1C3, AKR1C1, AKR1C4, AKR1A1, AKR1C2, AKR1B15, AKR1B10, KCNAB2, AKR7L, AKR1D1 |
| Tissue | testis |
| Tissue Specificity | Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078). {ECO:0000269|PubMed:12604216, ECO:0000269|PubMed:15118078}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35429729 rs17133693 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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