| Gene Information | |
|---|---|
| Gene Name | AKR1B15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 316 |
| Protein Names | Aldo-keto reductase family 1 member B15 (EC 1.1.1.-) (EC 1.1.1.300) (EC 1.1.1.54) (Estradiol 17-beta-dehydrogenase AKR1B15) (Farnesol dehydrogenase) (EC 1.1.1.216) (Testosterone 17beta-dehydrogenase) (EC 1.1.1.64) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000227471 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | C9JRZ8 |
| Gene Card | AKR1B15 |
| Uniprot ID | C9JRZ8 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | no (-0.455834601) |
| Ortholog in Animals | Alpaca_ AKR1B15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKR1C8, AKR7A3, KCNAB1, KCNAB3, AKR7A2, AKR1C3, AKR1C1, AKR1B1, AKR1E2, AKR1C4, AKR1A1, AKR1C2, AKR1B10, KCNAB2, AKR7L, AKR1D1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at highest levels in steroid-sensitive tissues, such as placenta, testis and adipose tissue. {ECO:0000269|PubMed:25577493}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion {ECO:0000269|PubMed:25577493}.; [Isoform 2]: Cytoplasm, cytosol {ECO:0000269|PubMed:25577493}. |
| Mouse PG classification | NA |
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