| Gene Information | |
|---|---|
| Gene Name | AKR1B11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 316 |
| Protein Names | Aldo-keto reductase family 1 member B10 (EC 1.1.1.300) (EC 1.1.1.54) (ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60218 |
| Gene Card | AKR1B10 |
| Uniprot ID | O60218 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. {ECO:0000269|PubMed:9565553}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1ZUA (X-ray 1.25A ) 4GA8 (X-ray 1.94A ) 4GAB (X-ray 1.60A ) 4GQ0 (X-ray 2.10A ) 4GQG (X-ray 1.92A ) 4I5X (X-ray 2.10A ) 4ICC (X-ray 1.75A ) 4JIH (X-ray 2.30A ) 4JII (X-ray 2.20A ) 4WEV (X-ray 1.45A ) 4XZL (X-ray 1.70A ) 4XZM (X-ray 1.75A ) 4XZN (X-ray 1.70A ) 5LIK (X-ray 2.05A ) 5LIU (X-ray 1.75A ) 5LIW (X-ray 1.75A ) 5LIX (X-ray 1.95A ) 5LIY (X-ray 2.05A ) 5M2F (X-ray 1.50A ) 5Y7N (X-ray 2.50A ) |
| DBSNP | rs2303312 rs3735042 rs4728329 |
| Subcellular location [CC] | Lysosome {ECO:0000269|PubMed:21585341}. Secreted {ECO:0000269|PubMed:21585341}. Note=Secreted through a lysosome-mediated non-classical pathway. |
| Mouse PG classification | NA |
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