| Gene Information | |
|---|---|
| Gene Name | PADI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 664 |
| Protein Names | Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III) |
| Target Name | protein-arginine deiminase type-3 |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000142619 ) 3 ( ENSG00000280549 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9ULW8 |
| Gene Card | PADI3 |
| Uniprot ID | Q9ULW8 |
| Pfam | PF03068; PF08527; PF08526 |
| In ASD | no |
| Allosteric Prediction | no (-0.600731723) |
| Ortholog in Animals | Alpaca_ PADI3 ( ortholog_one2one ) GuineaPig_ PADI3 ( ortholog_one2one ) Macaque_ PADI3 ( ortholog_one2one ) Mouse_ Padi3 ( ortholog_one2one ) Pig_ PADI3 ( ortholog_one2one ) Rat_ Padi3 ( ortholog_one2one ) Rabbit_ PADI3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PADI6, PADI4, PADI1, PADI2 |
| Tissue | urinary.bladder |
| Tissue Specificity | Hair follicles, and epidermis at very low levels. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CE1 (X-ray 2.80A ) 7D4Y (X-ray 2.96A ) 7D56 (X-ray 3.17A ) 7D5R (X-ray 3.15A ) 7D5V (X-ray 2.10A ) 7D8N (X-ray 2.75A ) 7DAN (X-ray 3.10A ) |
| DBSNP | rs3750300 rs142129409 rs2272629 rs144080386 rs781009577 rs34097903 rs144944758 rs35624745 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27866708}. |
| Mouse PG classification | HPG |
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