| Gene Information | |
|---|---|
| Gene Name | FASTKD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 847 |
| Protein Names | FAST kinase domain-containing protein 1, mitochondrial |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000138399 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q53R41 |
| Gene Card | FASTKD1 |
| Uniprot ID | Q53R41 |
| Pfam | PF06743; PF08368; PF08373 |
| In ASD | no |
| Allosteric Prediction | no (-1.054747767) |
| Ortholog in Animals | Alpaca_ FASTKD1 ( ortholog_one2one ) Dog_ FASTKD1 ( ortholog_one2one ) GuineaPig_ FASTKD1 ( ortholog_one2one ) Macaque_ FASTKD1 ( ortholog_one2one ) Mouse_ Fastkd1 ( ortholog_one2one ) Pig_ FASTKD1 ( ortholog_one2one ) Rat_ Fastkd1 ( ortholog_one2one ) Rabbit_ FASTKD1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FASTK, FASTKD3, TBRG4, FASTKD2, FASTKD5 |
| Tissue | NA |
| Tissue Specificity | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart. {ECO:0000269|PubMed:20869947}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12618227 rs35106223 rs2253680 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:20869947, ECO:0000269|PubMed:28238724, ECO:0000269|PubMed:28335001}. Note=Preferentially localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly (PubMed:28335001). {ECO:0000269|PubMed:28335001}. |
| Mouse PG classification | NA |
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