| Gene Information | |
|---|---|
| Gene Name | AKAP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 854 |
| Protein Names | A-kinase anchor protein 4 (AKAP-4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI) (Protein kinase A-anchoring protein 4) (PRKA4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000147081 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q5JQC9 |
| Gene Card | AKAP4 |
| Uniprot ID | Q5JQC9 |
| Pfam | PF05716; PF10522 |
| In ASD | no |
| Allosteric Prediction | no (-0.851974197) |
| Ortholog in Animals | Alpaca_ AKAP4 ( ortholog_one2one ) Dog_ AKAP4 ( ortholog_one2one ) GuineaPig_ AKAP4 ( ortholog_one2one ) Macaque_ AKAP4 ( ortholog_one2one ) Mouse_ Akap4 ( ortholog_one2one ) Pig_ AKAP4 ( ortholog_one2one ) Rat_ Akap4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKAP3, AKAP11, SPHKAP |
| Tissue | testis |
| Tissue Specificity | Testis specific; only expressed in round spermatids. {ECO:0000269|PubMed:9514854}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17174078 rs12012704 |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:9822690}. Note=Localizes to the principle piece of the sperm flagellum. |
| Mouse PG classification | NA |
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