| Gene Information | |
|---|---|
| Gene Name | AKAP11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1901 |
| Protein Names | A-kinase anchor protein 11 (AKAP-11) (A-kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220) (Protein kinase A-anchoring protein 11) (PRKA11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000023516 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKA4 |
| Gene Card | AKAP11 |
| Uniprot ID | Q9UKA4 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.667810514) |
| Ortholog in Animals | Alpaca_ AKAP11 ( ortholog_one2one ) Dog_ AKAP11 ( ortholog_one2one ) GuineaPig_ AKAP11 ( ortholog_one2one ) Macaque_ AKAP11 ( ortholog_one2one ) Mouse_ Akap11 ( ortholog_one2one ) Pig_ AKAP11 ( ortholog_one2one ) Rat_ Akap11 ( ortholog_one2one ) Rabbit_ AKAP11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPHKAP, AKAP4, AKAP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal muscle, pancreas and spleen. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2236364 rs17063163 rs17063167 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm. |
| Mouse PG classification | NA |
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