| Gene Information | |
|---|---|
| Gene Name | BPIFC |
| Organism | Homo sapiens (Human) |
| Gene Length | 507 |
| Protein Names | BPI fold-containing family C protein (Bactericidal/permeability-increasing protein-like 2) (BPI-like 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000184459 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NFQ6 |
| Gene Card | BPIFC |
| Uniprot ID | Q8NFQ6 |
| Pfam | PF01273; PF02886 |
| In ASD | no |
| Allosteric Prediction | no (-1.628142012) |
| Ortholog in Animals | Alpaca_ BPIFC ( ortholog_one2one ) Dog_ BPIFC ( ortholog_one2one ) GuineaPig_ BPIFC ( ortholog_one2one ) Macaque_ BPIFC ( ortholog_one2one ) Mouse_ Bpifc ( ortholog_one2one ) Pig_ BPIFC ( ortholog_one2one ) Rat_ Bpifc ( ortholog_one2one ) |
| Ohnologs | PLTP, BPI, LBP |
| Paralogs | BPI, LBP, PLTP, CETP, BPIFB2, BPIFB6, BPIFB4, BPIFB3, BPIFA2, BPIFA1, BPIFA3, BPIFB1 |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Detected in the basal layer of the epidermis from inflammatory skin from psoriasis patients, but not in normal skin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2076051 rs5994570 rs5998478 rs35856742 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:P17213}. |
| Mouse PG classification | NA |
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