| Gene Information | |
|---|---|
| Gene Name | AJAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | Adherens junction-associated protein 1 (Membrane protein shrew-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000196581 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UKB5 |
| Gene Card | AJAP1 |
| Uniprot ID | Q9UKB5 |
| Pfam | PF15298 |
| In ASD | no |
| Allosteric Prediction | no (-1.312984451) |
| Ortholog in Animals | Alpaca_ AJAP1 ( ortholog_one2one ) Dog_ AJAP1 ( ortholog_one2one ) GuineaPig_ AJAP1 ( ortholog_one2one ) Macaque_ AJAP1 ( ortholog_one2one ) Mouse_ Ajap1 ( ortholog_one2one ) Pig_ AJAP1 ( ortholog_one2one ) Rat_ Ajap1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in uterus and pancreas (at protein level). {ECO:0000269|PubMed:14595118}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs242056 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:16707570}; Single-pass type I membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:16707570}; Single-pass type I membrane protein {ECO:0000255}. Cell junction, adherens junction {ECO:0000269|PubMed:14595118}. Note=Mainly basolateral (PubMed:16707570). Localization is mediated by AP1M2 (PubMed:16707570). {ECO:0000269|PubMed:16707570}. |
| Mouse PG classification | NA |
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