| Gene Information | |
|---|---|
| Gene Name | AIRM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 467 |
| Protein Names | Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y286 |
| Gene Card | SIGLEC7 |
| Uniprot ID | Q9Y286 |
| Pfam | PF13895; PF07686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed by resting and activated natural killer cells and at lower levels by granulocytes and monocytes. High expression found in placenta, liver, lung, spleen, and peripheral blood leukocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1NKO (X-ray 1.45A ) 1O7S (X-ray 1.75A ) 1O7V (X-ray 1.90A ) 2DF3 (X-ray 1.90A ) 2G5R (X-ray 1.60A ) 2HRL (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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