| Gene Information | |
|---|---|
| Gene Name | AIPL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Aryl-hydrocarbon-interacting protein-like 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000129221 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NZN9 |
| Gene Card | AIPL1 |
| Uniprot ID | Q9NZN9 |
| Pfam | PF00254 |
| In ASD | no |
| Allosteric Prediction | no (-0.471349283) |
| Ortholog in Animals | Alpaca_ AIPL1 ( ortholog_one2one ) Dog_ AIPL1 ( ortholog_one2one ) GuineaPig_ AIPL1 ( ortholog_one2one ) Macaque_ AIPL1 ( ortholog_one2one ) Mouse_ Aipl1 ( ortholog_one2one ) Pig_ AIPL1 ( ortholog_one2one ) Rat_ Aipl1 ( ortholog_one2one ) Rabbit_ AIPL1 ( ortholog_one2one ) |
| Ohnologs | AIP |
| Paralogs | AIP |
| Tissue | pineal.gland |
| Tissue Specificity | Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina. {ECO:0000269|PubMed:12374762}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5U9A (X-ray 2.70A ) 5U9I (X-ray 2.30A ) 5U9J (X-ray 2.10A ) 5U9K (X-ray 2.70A ) 5V35 (X-ray 2.50A ) 6PX0 (X-ray 1.55A ) |
| DBSNP | rs16955859 rs12449580 rs16955851 rs62637012 rs62637015 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12374762}. Nucleus {ECO:0000269|PubMed:12374762}. |
| Mouse PG classification | HPG |
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