| Gene Information | |
|---|---|
| Gene Name | AIMP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein JTV-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000106305 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13155 |
| Gene Card | AIMP2 |
| Uniprot ID | Q13155 |
| Pfam | PF16780; PF14497; PF18569 |
| In ASD | yes |
| Allosteric Prediction | no (-0.338634848) |
| Ortholog in Animals | Alpaca_ AIMP2 ( ortholog_one2many ) Dog_ AIMP2 ( ortholog_one2one ) GuineaPig_ AIMP2 ( ortholog_one2one ) Macaque_ AIMP2 ( ortholog_one2one ) Mouse_ Aimp2 ( ortholog_one2one ) Pig_ AIMP2 ( ortholog_one2one ) Rat_ Aimp2 ( ortholog_one2one ) Rabbit_ AIMP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.049426(Rat);0.058618(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DPG (X-ray 2.84A ) 4YCU (X-ray 2.10A ) 4YCW (X-ray 2.90A ) 5A1N (X-ray 2.10A ) 5A34 (X-ray 2.60A ) 5A5H (X-ray 2.32A ) 5Y6L (X-ray 2.90A ) 6ILD (X-ray 1.88A ) 6IY6 (X-ray 3.60A ) 6JPV (X-ray 2.15A ) 6K39 (X-ray 1.40A ) |
| DBSNP | rs17855441 rs34525431 rs982080297 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:19289464}. Nucleus {ECO:0000250|UniProtKB:Q8R010}. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. {ECO:0000250|UniProtKB:Q8R010}. |
| Mouse PG classification | NA |
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