| Gene Information | |
|---|---|
| Gene Name | AIG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Androgen-induced gene 1 protein (AIG-1) (Fatty acid esters of hydroxy fatty acids hydrolase AIG1) (FAHFA hydrolase AIG1) (EC 3.1.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000146416 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NVV5 |
| Gene Card | AIG1 |
| Uniprot ID | Q9NVV5 |
| Pfam | PF04750 |
| In ASD | no |
| Allosteric Prediction | no (-1.501100288) |
| Ortholog in Animals | Alpaca_ AIG1 ( ortholog_one2one ) Dog_ AIG1 ( ortholog_one2one ) GuineaPig_ AIG1 ( ortholog_one2one ) Macaque_ AIG1 ( ortholog_one2one ) Mouse_ Aig1 ( ortholog_one2one ) Pig_ AIG1 ( ortholog_one2one ) Rat_ Aig1 ( ortholog_one2one ) Rabbit_ AIG1 ( ortholog_one2one ) |
| Ohnologs | ADTRP |
| Paralogs | ADTRP |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, ovary, testis, liver, and kidney, at lower levels in spleen, prostate, brain, skeletal muscle, pancreas, small intestine and colon, and undetected in peripheral blood leukocytes, thymus, lung and placenta. AIG1 expression is higher in hair follicles from males than from females. {ECO:0000269|PubMed:11266118}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1053193 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:27018888}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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