| Gene Information | |
|---|---|
| Gene Name | DNER |
| Organism | Homo sapiens (Human) |
| Gene Length | 737 |
| Protein Names | Delta and Notch-like epidermal growth factor-related receptor |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000187957 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NFT8 |
| Gene Card | DNER |
| Uniprot ID | Q8NFT8 |
| Pfam | PF19330; PF00008; PF12661 |
| In ASD | no |
| Allosteric Prediction | no (-0.492623187) |
| Ortholog in Animals | Alpaca_ DNER ( ortholog_one2one ) Dog_ DNER ( ortholog_one2one ) GuineaPig_ DNER ( ortholog_one2one ) Macaque_ DNER ( ortholog_one2one ) Mouse_ Dner ( ortholog_one2one ) Pig_ DNER ( ortholog_one2one ) Rat_ Dner ( ortholog_one2one ) Rabbit_ DNER ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NOTCH4, JAG1, DLL4, JAG2, DLL1 |
| Tissue | adrenal.gland, brain, cerebral.cortex |
| Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. {ECO:0000269|PubMed:11997712}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17853365 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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