| Gene Information | |
|---|---|
| Gene Name | AHSG |
| Organism | Homo sapiens (Human) |
| Gene Length | 367 |
| Protein Names | Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B] |
| Target Name | connecting peptide |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000145192 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P02765 |
| Gene Card | AHSG |
| Uniprot ID | P02765 |
| Pfam | PF00031 |
| In ASD | no |
| Allosteric Prediction | yes (0.777647837) |
| Ortholog in Animals | Alpaca_ AHSG ( ortholog_one2one ) Dog_ AHSG ( ortholog_one2one ) GuineaPig_ AHSG ( ortholog_one2one ) Macaque_ AHSG ( ortholog_one2one ) Mouse_ Ahsg ( ortholog_one2one ) Pig_ AHSG ( ortholog_one2one ) Rat_ AABR07034632.1 ( ortholog_one2one ) Rabbit_ AHSG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HRG, KNG1, FETUB |
| Tissue | liver, brain |
| Tissue Specificity | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7633550 rs4917 rs4918 rs70961709 rs35457250 rs201849460 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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