| Gene Information | |
|---|---|
| Gene Name | INKA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | PAK4-inhibitor INKA1 (Induced in neural crest by AP2-alpha protein homolog) (HInca) (Inka box actin regulator 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000185614 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96EL1 |
| Gene Card | INKA1 |
| Uniprot ID | Q96EL1 |
| Pfam | PF15342 |
| In ASD | no |
| Allosteric Prediction | no (-1.812747131) |
| Ortholog in Animals | Alpaca_ INKA1 ( ortholog_one2one ) Dog_ INKA1 ( ortholog_one2one ) GuineaPig_ INKA1 ( ortholog_one2one ) Macaque_ INKA1 ( ortholog_one2one ) Mouse_ Inka1 ( ortholog_one2one ) Pig_ INKA1 ( ortholog_one2one ) Rat_ Inka1 ( ortholog_one2one ) Rabbit_ INKA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | INKA2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XBR (X-ray 2.94A ) 4XBU (X-ray 2.06A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26607847}. Cytoplasm {ECO:0000269|PubMed:26607847}. Note=Mainly nuclear (PubMed:26607847). Relocalizes to the cytoplasm following interaction with PAK4 (PubMed:26607847). {ECO:0000269|PubMed:26607847}. |
| Mouse PG classification | NA |
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