| Gene Information | |
|---|---|
| Gene Name | AHCTF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2266 |
| Protein Names | Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000153207 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WYP5 |
| Gene Card | AHCTF1 |
| Uniprot ID | Q8WYP5 |
| Pfam | PF13934; PF16687 |
| In ASD | no |
| Allosteric Prediction | no (-0.477426845) |
| Ortholog in Animals | Alpaca_ AHCTF1 ( ortholog_one2one ) Dog_ AHCTF1 ( ortholog_one2one ) GuineaPig_ AHCTF1 ( ortholog_one2one ) Macaque_ AHCTF1 ( ortholog_one2one ) Mouse_ Ahctf1 ( ortholog_one2one ) Pig_ AHCTF1 ( ortholog_one2one ) Rat_ Ahctf1 ( ortholog_one2one ) Rabbit_ AHCTF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7R5K (EM 12.00A ) |
| DBSNP | rs2642990 rs12410563 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8CJF7}. Nucleus {ECO:0000269|PubMed:17098863, ECO:0000269|PubMed:27341616}. Nucleus envelope {ECO:0000269|PubMed:17098863, ECO:0000269|PubMed:27341616}. Nucleus matrix {ECO:0000269|PubMed:17098863}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17098863, ECO:0000269|PubMed:27341616}. Nucleus, nucleoplasm {ECO:0000269|PubMed:17098863}. Nucleus, nuclear pore complex {ECO:0000269|PubMed:17098863}. Note=Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase. {ECO:0000269|PubMed:17098863}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |