| Gene Information | |
|---|---|
| Gene Name | AGTR1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P30556 |
| Gene Card | AGTR1 |
| Uniprot ID | P30556 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Liver, lung, adrenal and adrenocortical adenomas. {ECO:0000269|PubMed:1378723}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4YAY (X-ray 2.90A ) 4ZUD (X-ray 2.80A ) 6DO1 (X-ray 2.90A ) 6OS0 (X-ray 2.90A ) 6OS1 (X-ray 2.79A ) 6OS2 (X-ray 2.70A ) |
| DBSNP | rs12721226 rs17852013 rs12721225 rs104893677 rs1064533 rs1801021 rs17852012 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:33713620}; Multi-pass membrane protein {ECO:0000269|PubMed:25913193, ECO:0000269|PubMed:26420482, ECO:0000269|PubMed:30639100, ECO:0000269|PubMed:32079768}. |
| Mouse PG classification | NA |
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