| Gene Information | |
|---|---|
| Gene Name | FLVCR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 526 |
| Protein Names | Feline leukemia virus subgroup C receptor-related protein 2 (Calcium-chelate transporter) (CCT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000119686 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UPI3 |
| Gene Card | FLVCR2 |
| Uniprot ID | Q9UPI3 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | yes (0.031881908) |
| Ortholog in Animals | Alpaca_ FLVCR2 ( ortholog_one2one ) Dog_ FLVCR2 ( ortholog_one2one ) GuineaPig_ FLVCR2 ( ortholog_one2one ) Macaque_ FLVCR2 ( ortholog_one2one ) Mouse_ Flvcr2 ( ortholog_one2one ) Pig_ FLVCR2 ( ortholog_one2one ) Rat_ Flvcr2 ( ortholog_one2one ) Rabbit_ FLVCR2 ( ortholog_one2one ) |
| Ohnologs | FLVCR1 |
| Paralogs | FLVCR1, CFAP276, SLC49A4, SLC49A3 |
| Tissue | NA |
| Tissue Specificity | Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2287015 rs267606823 rs267606824 rs267606822 rs267606825 rs267606825 rs35126362 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | LPG |
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