Gene Information
Gene NameAGPAT5
OrganismHomo sapiens (Human)
Gene Length364
Protein Names1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000155189 )
3 ( ENSG00000284980 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9NUQ2
Gene CardAGPAT5
Uniprot IDQ9NUQ2
PfamPF16076; PF01553
In ASDno
Allosteric Predictionno (-1.086857094)
Ortholog in AnimalsAlpaca_ AGPAT5 ( ortholog_one2one )
Dog_ AGPAT5 ( ortholog_one2one )
GuineaPig_ AGPAT5 ( ortholog_one2one )
Macaque_ AGPAT5 ( ortholog_one2one )
Mouse_ Agpat5 ( ortholog_one2one )
Pig_ AGPAT5 ( ortholog_one2one )
Rat_ Agpat5 ( ortholog_one2one )
OhnologsNA
ParalogsLPGAT1, AGPAT4, AGPAT3, LCLAT1
Tissuepituitary.gland, placenta, testis
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:21173190}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17077958 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:21173190};
Multi-pass membrane protein {ECO:0000255}. Nucleus envelope {ECO:0000269|PubMed:21173190}. Mitochondrion {ECO:0000269|PubMed:21173190}.
Mouse PG classificationNA
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