| Gene Information | |
|---|---|
| Gene Name | AGPAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 378 |
| Protein Names | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000026652 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NRZ5 |
| Gene Card | AGPAT4 |
| Uniprot ID | Q9NRZ5 |
| Pfam | PF16076; PF01553 |
| In ASD | no |
| Allosteric Prediction | no (-1.23012926) |
| Ortholog in Animals | Alpaca_ AGPAT4 ( ortholog_one2one ) Dog_ AGPAT4 ( ortholog_one2one ) GuineaPig_ AGPAT4 ( ortholog_one2one ) Macaque_ AGPAT4 ( ortholog_one2one ) Mouse_ Agpat4 ( ortholog_one2one ) Pig_ AGPAT4 ( ortholog_one2one ) Rat_ Agpat4 ( ortholog_one2one ) |
| Ohnologs | AGPAT3 |
| Paralogs | AGPAT3, AGPAT5, LPGAT1, LCLAT1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus. {ECO:0000269|PubMed:21173190}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8K4X7}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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